Protein Destroying Muscle, Bone, Nerves Parks on Mitochondria
A failure to dispose of underperforming mitochondria may underlie the complex degenerative disorder known as multisystem proteinopathy...
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A failure to dispose of underperforming mitochondria may underlie the complex degenerative disorder known as multisystem proteinopathy...
if Charlie Glabe is right, an exploding neuron does expel material that then triggers the formation of new, stable matter in its surroundings...
Tau, α-Synuclein Spread: Crazy Stuff—How Might It Work? Like Star Born of Supernova, Plaque Born of Exploded Neuron? Can Dousing PyroGlu-Aβ Treat Alzheimer’s Disease? Field Ramps Up "Mini" Mouse MRI LRRK Watchers’ Eyes Turn to Inflammation, Auto
Last summer's news that a mutation in the amyloid precursor protein protects carriers against Alzheimer's disease made a big splash...
Many researchers believe that neurodegeneration's takeover of one's brain might be driven by pathogenic, misfolded proteins spreading through interconnected neural networks...
Growing evidence suggests that neurons begin faltering decades before cognitive symptoms in AD, but identifying the molecular culprits at play has proven challenging...
Among global initiatives aimed at understanding how biomarkers elucidate the progression of Alzheimer’s disease, DESCRIPA appears to do much with little...
Researchers have tried to tie M1 and M2 status to pathology in neurodegenerative diseases, but leaders in neuroinflammation are beginning to question their usefulness...
In the first GWAS based on amyloid imaging, researchers have uncovered single nucleotide polymorphisms near the genes encoding butyrylcholinesterase (BChE) and ApoE...
Researchers report that mutations in hnRNPA2B1 and hnRNPA1 cause amyotrophic lateral sclerosis and multisystem proteinopathy...
Researchers report that knocking out the zebrafish orthologues of TDP-43 damages organ systems, rendering the embryos not viable...
Exploring Genome Fragmentation in Neurodegeneration Up-and-Coming ALS Mice Leave Scientists ConFUSed Does ALS Gene Police RNA, Keep Strands From Entangling? Does New Amyloid Protein Lend Tau a Hand? Keystone Symposium: New Frontiers in Neurodegenerative D
Glutamate receptors at the postsynaptic membrane play important roles in neural plasticity...
In people with Alzheimer’s and AD model mice, tau appears to have a partner in EF Hand 2 (EFhd2)...
Researchers report that they can visualize the "glymphatic pathway" in rat brains by using contrast-enhanced magnetic resonance imaging...