Can Brain Metabolism Predict Huntington’s Symptoms?
People who carry the Huntington’s gene develop progressively abnormal brain metabolism a decade or more before diagnosis.
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People who carry the Huntington’s gene develop progressively abnormal brain metabolism a decade or more before diagnosis.
The Alzheimer’s Disease Neuroimaging Initiative has released whole genome sequences from 809 study volunteers.
Interested in Parkinson's? Apply for access to data and tissue samples, and funds to study them, from the Michael J. Fox Foundation.
By tracking Alzheimer’s research funding internationally, a new database could help sponsors coordinate research efforts.
In the first study of its kind, researchers found a surprisingly low incidence of Lewy body dementias in a U.S. population.
A new RNA interference therapy for amyotrophic lateral sclerosis has some success in mice and monkeys.
Advances in RNA sequencing are shedding light on gene regulation and helping scientists make sense of data from genome-wide association studies.
Rare mutations in the ADAM10 gene make a genetic case for the amyloid cascade as a cause of late onset Alzheimer's disease.
What’s better for future treatment of Parkinson’s: patient-derived or banked iPSCs? In comparison, patient’s own come out on top.
Antibodies against extracellular tau block seeding, diminish brain pathology, and may improve cognition in a mouse model.
Proposed preclinical stages for Alzheimer’s disease predict well who is most likely to progress to Alzheimer’s dementia.
It's not just for neurodevelopment anymore. Death receptor 6—known for pruning axons—also trims unused connections in adulthood, hinting at a function in Alzheimer's.
The NIH announced $45 million in new funding to support trials in preclinical Alzheimer’s populations, as well as efforts to identify new therapeutic targets.
New research proposes a neuroimmune receptor as the latest Aβ binding partner.
The first report on PBB3, the latest tau ligand for brain imaging under development, suggests it binds all types of tau aggregate.