Disease Mutations Zip Lock Stress Granules in Proteinopathy, ALS
Researchers report that mutations in hnRNPA2B1 and hnRNPA1 cause amyotrophic lateral sclerosis and multisystem proteinopathy...
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Researchers report that mutations in hnRNPA2B1 and hnRNPA1 cause amyotrophic lateral sclerosis and multisystem proteinopathy...
Researchers report that knocking out the zebrafish orthologues of TDP-43 damages organ systems, rendering the embryos not viable...
Exploring Genome Fragmentation in Neurodegeneration Up-and-Coming ALS Mice Leave Scientists ConFUSed Does ALS Gene Police RNA, Keep Strands From Entangling? Does New Amyloid Protein Lend Tau a Hand? Keystone Symposium: New Frontiers in Neurodegenerative D
Glutamate receptors at the postsynaptic membrane play important roles in neural plasticity...
In people with Alzheimer’s and AD model mice, tau appears to have a partner in EF Hand 2 (EFhd2)...
Researchers report that they can visualize the "glymphatic pathway" in rat brains by using contrast-enhanced magnetic resonance imaging...
Shutting off transgenic Aβ production in middle-aged mice whose brains are jam-packed with amyloid pathology was able to rescue some aspects of cognition...
Like a knot in your shoelace, entwined mRNAs can interfere with the nucleic acid’s normal actions...
Crystals of a bapineuzumab-Aβ complex may explain how the antibody targets amyloid plaques in the brain...
Mouse engineers presented the latest models overexpressing the amyotrophic lateral sclerosis gene fused in sarcoma (FUS)...
Researchers gathered in Santa Fe, New Mexico, for the Keystone Symposium “New Frontiers in Neurodegenerative Disease Research”...
When it comes to vascular brain injury, the dementia field has been mired in uncertainty...
A group of scientists proposes an ambitious project to map the activity of every neuron in the brain, and correlate the data with behavior and disease states...
Research solidifies the case that human neurons made from reprogrammed patient cells can help scientists unravel pathological mechanisms behind Alzheimer's disease...
In 2008, methylene blue created a stir when the drug’s sponsors reported that it slowed cognitive decline, while other scientists questioned that interpretation...