Spinal Fluid Flush: Visualizing the Brain Drain With MRI
Researchers report that they can visualize the "glymphatic pathway" in rat brains by using contrast-enhanced magnetic resonance imaging...
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Researchers report that they can visualize the "glymphatic pathway" in rat brains by using contrast-enhanced magnetic resonance imaging...
Shutting off transgenic Aβ production in middle-aged mice whose brains are jam-packed with amyloid pathology was able to rescue some aspects of cognition...
Like a knot in your shoelace, entwined mRNAs can interfere with the nucleic acid’s normal actions...
Crystals of a bapineuzumab-Aβ complex may explain how the antibody targets amyloid plaques in the brain...
Mouse engineers presented the latest models overexpressing the amyotrophic lateral sclerosis gene fused in sarcoma (FUS)...
Researchers gathered in Santa Fe, New Mexico, for the Keystone Symposium “New Frontiers in Neurodegenerative Disease Research”...
When it comes to vascular brain injury, the dementia field has been mired in uncertainty...
A group of scientists proposes an ambitious project to map the activity of every neuron in the brain, and correlate the data with behavior and disease states...
Research solidifies the case that human neurons made from reprogrammed patient cells can help scientists unravel pathological mechanisms behind Alzheimer's disease...
In 2008, methylene blue created a stir when the drug’s sponsors reported that it slowed cognitive decline, while other scientists questioned that interpretation...
In the AD field, most readers can count on one hand the companies that are widely known to have at least two drugs in sufficiently advanced stages to test combinations...
Just days after the first report of a highly eccentric translation mechanism in the major genetic forms of ALS and FTLD comes a second paper showing the same phenomenon...
White blood cells age quickly in post-menopausal women who carry the ApoE4 gene, but estrogen slows that decline...
Alzheimer's disease clinicians who have read the FDA's draft guidance on developing drug combinations consider it too vague to design trials with it...
Research suggests that deep-brain stimulation (DBS) can help at earlier stages—before motor complications get out of control...