Improving Cognition in Mice: Copper Ionophore Shows Some Mettle
PBT2, a zinc/copper ligand that may act like an ionophore, shows dramatic effects on cognition in transgenic mouse models of AD...
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PBT2, a zinc/copper ligand that may act like an ionophore, shows dramatic effects on cognition in transgenic mouse models of AD...
Presenilins may now have a new claim to fame...
Alternative splicing of messenger RNAs can result in the production of protein isoforms with different functions...
Overproduction seems to be a major problem for neurons...
From yeast to mammals, the realization that calorie restriction (CR) increases lifespan led to the mantra “eat less—live longer”...
New data on an assortment of therapeutic possibilities appear this week...
Paris: Intracellular Traffic and Neurodegenerative Disorders Ipsen Colloquium on Alzheimer’s Disease 2008
The inside of a cell is a very busy place...
Flurizan has floundered in an 18-month Phase 3 clinical trial in patients with mild Alzheimer disease...
There is an inherent dilemma in how best to ensure protection for cognitively vulnerable subjects without impeding research...
One way of catching up on what the ASG is doing to support the nation’s fight against AD is to read the companion story...
In response to rising calls for action, last year, the Alzheimer’s Study Group (ASG) was formed...
Compared with decades past, the clinical pipeline for investigational Alzheimer disease therapies is ready to burst...
Polyphenols, plant compounds found in abundance in red wine and green tea, fight Aβ aggregation...
An anti-inflammatory drug has shown therapeutic promise in a mouse model of Alzheimer disease...