ADNI: Mission Creep From Alzheimer Disease to Healthy Senior?
The Alzheimer’s Disease Neuroimaging Initiative (ADNI) was originally conceived as an exploratory project to identify the best measures for tracking disease progression...
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The Alzheimer’s Disease Neuroimaging Initiative (ADNI) was originally conceived as an exploratory project to identify the best measures for tracking disease progression...
Alzheimer imaging aficionados gathered for a peek at the latest data from the Alzheimer’s Disease Neuroimaging Initiative (ADNI)...
The oldest and the youngest people are often the most vulnerable to disease. The same might be true for cells...
The efficacy of Iplex is unknown; it is untested in clinical trials, untried in mouse models, and, for the most part, unapproved by the Food and Drug Administration...
The combined belt-and-suspenders approach is renowned for protecting against public humiliation, but it may hold up just as well when used in medicine...
Two recent papers offer clues as to how ALS progresses from onset to inevitable death...
Researchers add another dimension to BDNF biology. They report that CSF BDNF levels drop as people age and are lowest in those with poorest recall...
Amyloid-β (Aβ) oligomers are presumed guilty of killing neurons in Alzheimer disease, but that may not be their only transgression...
The earliest pathological underpinnings of Alzheimer disease often precede symptoms by untold numbers of years, presenting researchers with a two-edged sword...
Unfortunately, there is no quick test for predicting Alzheimer disease (AD)—at least not yet...
Though PIB has shown great promise as an in-vivo amyloid tracer in brain imaging, it is conceivable the compound does not pick up the full range of pathological Aβ in the brain...
Anyone who has grappled with a garden hose knows that it is much better behaved when it is coiled. The same could be said for DNA...
Mutations in tau cause the protein to aggregate in neurodegenerative diseases, but many conditions evince tau tangles in the absence of tau mutations...
People seem to have a heady relationship with the mental state called delirium...
The γ-secretase has come a long way since its original discovery as the protease responsible for the production of amyloid-β peptides during sequential cleavage of the amyloid precursor protein...