Exelon Dose Revised
According to a "Dear Healthcare Provider" letter dated January 26 and posted this week on the Web site of the U.S. Food and Drug Administration, patients who take breaks in Exelon...
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Study Finds Treatments for Agitation Are Inadequate
The drugs haloperidol or trazodone, or behavior management techniques (BMT), are commonly used to treat agitation in Alzheimer's patients...
AF102B (Cevimeline or Evoxac) Lowers CSF Aβ in Alzheimer Patients
A drug currently approved by the FDA for the treatment of dry mouth in Sjogren's syndrome (an autoimmune disease that affects excorine glands) has been shown to reduce levels of amyloid-β...
World Alzheimer Conference 2000: Symposium on Therapeutic Approaches
One of the first symposia of the conference was dedicated to an overview of the current and future treatments for AD. Six presenters gave their perspectives on many treatment issues...
World Alzheimer Conference 2000: Symposium on ApoE
Amyloid plaques are still the main attraction, and tangles have certainly not left the stage, but there is still a lot of interest at this meeting (off-Broadway, so to speak) in other potential players in AD pathology...
World Alzheimer Conference 2000: Maybe Plaques Kill Neurons after All
Although there are many reports of neurotoxic effects of amyloid when applied to neurons in culture, the evidence for toxicity in vivo has been...
World Alzheimer Conference 2000: Drosophilae in the Emulsifier
The centrality of the amyloid hypothesis for AD pathology is evident at the World Alzheimer Congress 2000, not only by the sheer number of papers and posters devoted to it, but also by...
World Alzheimer Conference 2000: Hot Topics in AD
Several late-breaking, dramatic results were presented at this final symposium of the World Alzheimer Congress 2000...
World Alzheimer Conference 2000: Amyloid Is Necessary and Sufficient to Cause Dementia
The scientific highlight of the Prof. Henry Wisniewski memorial symposium (12 July) was an informative lecture about familial British dementia (FBD)...
World Alzheimer Conference 2000: It’s Fibrillogenesis, Not the Fibrils!
Peter Lansbury, like I and others, has long promulgated the idea that intermediates in CNS disease-related fibrillogenesis processes are likely to be pathogenic, whereas mature matted fibrils (although not desirable) are relatively inert...
World Alzheimer Conference 2000: Presenilin's γ-Secretase Activity
Almost 12% (152) of the 1307 abstracts presented at the 7th International Conference on Alzheimer’s Disease and related disorders made reference to presenilin (PS)...
Ocean Waves Stimulate Brain Waves: Meeting Report from Caribbean
Last week, 80 researchers from Caribbean nations, the U.S., and countries in Europe, the Middle East, and Asia met in balmy Montego Bay, Jamaica, for a 5-day conference...
Are We Humans Really That Complex? Just Look at RNA Transcription
One of the big surprises of the genome project was the final tally of how many genes it takes to make a human...
ARF Advisor to Receive National Medal of Science
Ann Graybiel of the Massachusetts Institute of Technology, a member of the Alzheimer Research Forum's scientific advisory board since 1999, is one of 15 scientists...
American Society for Cell Biology 38th Annual Meeting, San Francisco, 12-16 December, 1998
A special interest subgroup meeting on 'Tau protein in Neurodegenerative Diseases' was organized by Gloria Lee, University of Iowa. This was a timely and stimulating meeting...
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