Copper Mountain: Can CREB Save Memory?
The Keystone Symposium at Copper Mountain, Colorado, was convened to discuss therapeutic approaches to Alzheimer disease besides those that target amyloid-β...
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The Keystone Symposium at Copper Mountain, Colorado, was convened to discuss therapeutic approaches to Alzheimer disease besides those that target amyloid-β...
TDP-43, normally a mild-mannered nuclear protein, morphs into a cytoplasmic super villain in TDP-43 proteinopathies...
For stem cell therapies to work, it is not enough for a new neuron to settle down in the brain...
Researchers have, by and large, assumed that Aβ starts aggregating outside the cell...
Two studies revive the notion that it might be possible, quite literally, to catch a whiff of neurodegenerative disease before the body and mind slip away for good...
Through their research participation, the Reiswig extended family made possible the identification of presenilin 2 on chromosome 1...
The Alzforum presents a selection of some of the top ALS trial news of 2009—and looks ahead to 2010 and beyond...
<em>Drosophila</em> geneticists with an interest in neurodegeneration can now avail themselves of a new insect model...
If your lab has been scrimping and saving lately, you are not alone...
Bending to joint pressure from Congress, doctors, and the media, the NFL recently took steps to protect players with head injuries and to bolster research...
Phone companies will love this one; a new paper suggests that electromagnetic fields (EMFs) from cell phones can protect against AD—at least in mice...
Charcot-Marie-Tooth disease and spinal muscular atrophy are united by similar symptoms of progressive motor neuron degeneration...
When it comes to slowing Aβ production in Alzheimer disease, blocking either β- or γ-secretase has proven effective but comes with nasty side effects...
With newly developed quantum-dot nanoprobes, scientists can now watch individual Aβ molecules glom together into oligomers and fibrils in real time...
Tweaking the signaling pathway between cyclic AMP (cAMP) and proteins involved in memory has the potential to treat a variety of cognitive disorders...