6392 RESULTS
Sort By:
The debate over the etiology of Parkinson's disease (PD) has been spurred by an article in the November 14 Journal of the American Medical Association, in which the authors contend that genetics, not just environmental factors...
Two papers published this week offer data that might further the search for therapies in neurodegenerative disease, particularly in Parkinson's...
The therapeutic potential of human stem cells seems a little more realistic, thanks to results published in this month's Nature Biotechnology. Two groups have succeeded in transplanting human neural progenitors into neonatal mice...
In the last four years, cancer researchers have come to realize that the lipid phosphatase PTEN is perhaps as important a tumor suppressor as its more famous cousin p53. At the same time, other researchers are trying to harness...
Just in time to ponder this weighty question comes a short communication in tomorrow's Nature. Martin Carrier and colleagues at the William Harvey Research Institute in London report that polyphenols in red wines potently inhibit expression of the vasoconstrictor peptide endothelin-1...
Though considerable effort has been spent over the last few decades investigating the relationship between Alzheimer's disease and aluminum, the role of the transition metal remains controversial...
Over the past decade, it has become clear that microorganisms are vastly more diverse and ubiquitous than our egocentric species ever thought possible. This has led some scientists to suspect that microbes may be causing human diseases...
Huntington's disease (HD) is caused by polyglutamine (polyQ) expansion within the huntingtin protein (Htt), but the sequence of events leading to neurodegeneration remains unclear...
Since it became clear that Alzheimer's disease has features in common with chronic inflammation, much effort has gone into determining whether the various inflammatory response molecules are helping to protect, or to destroy, vulnerable neurons...
Despite much research, it has been difficult to pin down precisely how inflammation contributes to Alzheimer's disease. This endeavor is now drawing fresh support from single nucleotide polymorphism (SNP) analysis...
The growth and development of transplantable neurons from embryonic stem (ES) cells could potentially have immense value for those suffering from neurodegenerative diseases...
The identity of γ-secretase, the aspartyl protease responsible for snipping amyloid-β (Aβ) from β-secretase-processed amyloid precursor protein (AβPP), has remained elusive for some time...
The loss of neurons associated with such diseases as Alzheimer's and Parkinson's have long been attributed to neural degeneration. But could this degeneration actually belie underlying problems in regeneration?...
The link between mild cognitive impairment and Alzheimer's disease pathology grows stronger with a study in this month's Annals of Neurology. Kathy Riley, David Snowdon, and William Markesbery of the University of Kentucky report a strong correlation...
Despite the recent setbacks in Elan's clinical trials, vaccines still have enormous potential as therapeutic agents for a variety of disorders. As reported last week at the American College of Cardiology's 51st annual scientific session in Atlanta...
