Stem Cell Advance—A Safer, Inducible Pluripotent Cell?
As drug makers try to rescue dying neurons, others hold out hope that supplying fresh ones may be a better way to combat Alzheimer and other neurodegenerative diseases...
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As drug makers try to rescue dying neurons, others hold out hope that supplying fresh ones may be a better way to combat Alzheimer and other neurodegenerative diseases...
Growing postmortem evidence suggests that repeated early-life concussion sets off a pathological cascade in the brain...
Robert Katzman was a pioneer in bringing Alzheimer disease out of obscurity and into the forefront of medical, scientific, and social agenda of this country...
Robert Katzman, a leader in the field of Alzheimer’s research, died at his home in La Jolla, California, last week...
Showing that an experimental Alzheimer’s therapy delivers meaningful cognitive change is hard enough...
Flagging mitochondria, the powerhouses of the cell, have been linked to general aging and also to a variety of neurodegenerative diseases...
The presence of small oligomeric protein assemblies with neurotoxic properties has become a common thread in several neurodegenerative diseases...
Experimental evidence and plain common sense tell us that neurons lose activity in Alzheimer disease...
At first glance, the pair of proteins that form the key pathological features of Alzheimer disease seem quite an odd couple...
Human memory is one of the last great biological mysteries...
Among the plethora of factors that might serve as useful biomarkers for AD, perhaps none draws as much scrutiny as plasma amyloid-β...
Recent work indicates that CSF BACE activity is significantly increased in people with AD...
Healthy aging relies on proper function of the transcription factor p53...
Hopping off the couch and into the gym helps both heart and mind, even in seniors at risk for dementia...
The hopes for treating AD by inhibiting the amyloid-producing enzyme β-secretase (BACE) rest largely on results obtained in mice...