Mitochondria Sag Early in AD Mouse Model
The energy needs of neurons are prodigious—the brain makes up just a small percentage of the body, yet burns roughly 25 percent of its calories...
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The energy needs of neurons are prodigious—the brain makes up just a small percentage of the body, yet burns roughly 25 percent of its calories...
Chances are, when asked to list possible causes for Parkinson and Alzheimer diseases, many scientists would not think to include flu virus...
Consider browsing this week’s JAMA over a glass of wine, because it may take time to digest and appreciate their nuanced conclusions...
Do we use it or lose it, or use it and lose it? If synaptic activity spurs Aβ production, why do education, environmental stimulation, and socialization all protect against AD?
Genomewide association studies reported by two groups converged on three hits for sporadic Alzheimer disease (AD), ApoJ, CR1, and PICALM...
Aggregates of α-synuclein are the principal component of Lewy bodies, neuronal inclusions found in Parkinson and other neurodegenerative diseases...
In the case of axonal transport, it may not be about who wins the race, but what’s carried to the finish line...
Synchrony and uniformity tend to characterize line dancers, but they may elude neurons when LINE-1 (long interspersed element 1) retrotransposons take the stage...
The theme “don’t go whole hog” might come to mind for those who check out two recent papers suggesting potential therapeutic strategies for Alzheimer disease...
Scientists continue to sound out new strategies for re-establishing broken neural connections and for protecting injured spinal cords from further damage...
Presenilin mutations cause familial Alzheimer disease, but just how they do their damage is not understood...
Uppsala: Immunotherapy and Biomarkers Take Center Stage Uppsala: Brainstorming Biomarkers Uppsala University, Sweden, played host to “Neurodegenerative Disorders—Immunotherapy and Biomarkers,” an international conference held 28-29 May 2009, and organized
A variety of approaches are beginning to home in on Aβ oligomers as drug targets, and some of them were showcased at the International Conference on Alzheimer’s Disease...
Whether Aβ amyloid portends future dementia isn’t so clear, but a report in the July 30 Neuron puts meat and bones on the hunch that it does...
Biomarkers were top of the agenda on the second day of Neurodegenerative Disorders—Immunotherapy and Biomarkers...