Less VAPid Now: Role for ALS Protein Gets Substance
Scientists are beginning to get a handle on a rare inherited form of amyotrophic lateral sclerosis (ALS)...
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Scientists are beginning to get a handle on a rare inherited form of amyotrophic lateral sclerosis (ALS)...
Clinical testing of ACC-001, Elan’s second-generation Aβ vaccine, is back on track...
When told what to kill, the complement system deftly deals the final blows...
A paper publishes data on an amyloid-lowering strategy that involves boosting the activity of the plasmin protease...
Mice with a defect in a mitochondrial dehydrogenase enzyme show age-related neurodegeneration...
Neurons may not have a monopoly on storing information in the brain...
Researchers present evidence that induction of miR132 contributes to dendrite growth...
With mounting evidence that AD can silently ravage the brain years before symptoms emerge, the race is on to develop compounds that can detect preclinical changes...
Genetic variants in the MAPT gene are associated with an earlier age of onset, but not with overall risk of AD...
Today, Elan and Wyeth announced preliminary results of one of their closely watched Phase 2 clinical trials of Bapineuzumab...
Despite its spot on top of the pile of genetic risk factors for late onset AD, ApoE has remained an enigma on the pathophysiological level...
A study offers unexpected insight into a class of drugs being explored for treatment of Alzheimer disease...
The prevalence of AD increases exponentially after age 65, but that doesn’t mean all people will get the disease...
In addition to cognitive decline, patients with advanced AD frequently have psychiatric problems...
Researchers led by Oskar Hansson at Lund University, Sweden, have developed a highly sensitive assay for plasma Aβ...