The simple act of opening an e-mail or saying “I love you” is out of reach for many people paralyzed by accident or disease, but 40 of them could get the chance to try out brain-computer interfaces...
The mutant protein that causes Huntington disease blocks axonal traffic by putting the molecular equivalent of the wheel-locking “boot” on motor proteins...
It’s enough to make a doctor’s head ache—antithrombotic drugs may protect people from stroke or heart attack, but the same medications may also increase risk of cerebral microbleeds...
Used largely as a last-ditch option for taming unruly motor symptoms in some PD patients, deep brain stimulation (DBS) might hold potential for treating dementia as well...
A new study strengthens the idea that Reelin, an extracellular matrix protein essential for brain development, works, at least in part, by binding APP...
The mechanisms linking insulin to neurodegeneration were examined at the Fondation IPSEN 24th annual colloquium on Alzheimer’s Disease, held in Paris on 6 April 2009...
Amyloid-β (Aβ) peptide oligomers have come under intense scrutiny as the prime suspects in the synapse loss and neurotoxicity associated with Alzheimer disease...
Amyotrophic lateral sclerosis, already a rare condition affecting one to three people in 100,000, nonetheless garners most of the attention in the field of motor neuron disease...
Calculating the risk of impending AD based on levels of CSF Aβ42 has been tricky because the peptide forms insoluble aggregates that muddle estimates of its production rate in the CNS...
A recent population-based study supports the idea that in the oldest old, the relationship between plaques and tangles, and dementia, may be more legend than substance...