In this month's Journal of Medical Genetics, a group of Italian researchers propose that there is a link between longevity and a single nucleotide polymorphism (SNP) in the promoter for the antiinflammatory cytokine interleukin-10 (IL-10)...
In the July 8 issue of Current Biology, researchers at the University of California, Los Angeles, and Kyoto University, Japan, reveal that mice carrying a mutated version of the Notch gene suffer from spatial learning and memory defects...
Several studies have shown that Alzheimer’s patients appear to be less susceptible to cancer, but the mechanism behind this association remains mysterious...
Researchers report that immediate versus gradual application of brain-derived neurotrophic factor (BDNF) has “dramatically” different results for cultured neurons...
Researchers led by Dennis Selkoe offer what he considers the “cleanest, best-controlled evidence to date” for the toxicity of small amyloid-β oligomers...
It appears that some tauopathies require the presence of neurofilaments for neurodegeneration to occur. In the 15 August Journal of Neuroscience, Virginia Lee, Takeshi Ishihara, and colleagues at the University of Pennsylvania describe...
Even though ApoE stands head and shoulders above other genetic risk factors for late-onset AD, few therapeutic strategies aimed at ApoE have made it to clinical trials...