Keystone: γ Slowly Relinquishes Its Secrets Keystone: Lipids Grease γ-Secretase Activity Keystone: Loss Versus Gain—Mutations a Drag on γ-Secretase Fiendishly complicated, γ-secretase has proved a formidable foe to the structurally minded scientist. But g
One of the big surprises at this year’s Human Amyloid Imaging meeting was the finding that a significant proportion of healthy controls are PIB-positive...
HAI Chicago: PIB in Healthy People HAI Chicago: Can PIB Predict Cognitive Decline? HAI Chicago: PIB and Aβ Show Regional Nuances and Sleep-Wake Rhythm HAI Chicago: Not Just PIB—Other PET Tracers in Clinical Pipeline Human Amyloid Imaging 2008
Two genetics papers this month add to the mounting evidence that TAR DNA binding protein (TDP-43) is a key player in ALS and not just an innocent bystander...
Blood levels of the antioxidant molecule urate are associated with the risk of progression in patients with Parkinson disease, according to a new study...
At the Keystone conference, researchers presented new data to argue that pyroglutamate (pGlu) derivatives of Aβ may be critically important in the underlying pathology of AD...
For the brave patients who elected to have foreign fetal neurons implanted in their brain as an experimental treatment for Parkinson disease (PD), there must have been many agonizing thoughts...