Fundamental knowledge gaps in Alzheimer disease research include a clear grasp of the normal role of the amyloid precursor protein (APP), and the molecular basis for the increased risk for AD as people age...
Thanks to a new imaging technology, researchers discovered that amyloid plaques can literally show up overnight and grow to their full size in just a few days...
To stop the destruction of neurons in Alzheimer disease requires an understanding of how the two protein perpetrators, amyloid-β and tau do their dirty work...
Transient episodes of neurological symptoms—muscle weakness, double vision, or other signs that last less than 24 hours—reveal underlying circulatory problems in the brain...
Part 1 of this story covered the growing evidence linking diabetes with Aβ pathology and cognition. But what about the other major hallmark of Alzheimer disease, neurofibrillary tangles?...