Yeast Screen Implicates PARK9 in Synuclein Toxicity
In Parkinson disease, death of dopaminergic neurons can result from mutations in one of several genes, environmental factors, and unknown causes...
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In Parkinson disease, death of dopaminergic neurons can result from mutations in one of several genes, environmental factors, and unknown causes...
A batch of new studies shifts the spotlight from neurons to astrocytes, revealing critical roles for these helper cells in Parkinson and Alzheimer diseases...
Modafinil was first found to increase cognitive functions in schizophrenic patients when it was used to counteract the sedative properties of atypical antipsychotics...
A person’s ability to recall memories year after year depends less on the brain’s hippocampus and more on its frontal, temporal, and parietal areas...
There’s a new player in town or, to be precise, in the rat brain...
Mutations in the gene encoding LRRK2 (aka tyrosine kinase leucine-rich repeat kinase 2) are the most common cause of hereditary Parkinson disease...
Understanding how genetic variation contributes to human disease has become a major thrust of modern science...
Cutting calories may be good for the brain as well as the waistline...
When proteins fail to curl up in the right conformation, molecular chaperones sort them out, or the misfits are tagged for destruction...
When Nigel Leigh started scanning the brains of people with ALS in the early 1990s, colleagues said he was wasting his time...
The New York Times yesterday continued its coverage of the contentious question of whether repeated sports concussions predispose a fraction of players to brain damage...
Two new papers add to growing evidence linking diabetes and neurodegenerative disease...
Iron is an essential cofactor in many metabolic processes, but it can also be a dangerous parcel...
Last week’s PNAS online describes some new gross anatomical and electrophysiological changes that accompany Alzheimer disease (AD) and frontotemporal dementia (FTD)...
The idea of the default mode network quickly became a hot topic in cognitive neuroscience and for Alzheimer disease researchers...