New Spin on γ-Secretase—Tangled in Tetraspanin Web?
A new study adds γ-secretase to the list of proteins that interact with tetraspanins...
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Clinical Trials on Alzheimer's Disease 2009
Las Vegas: New Partner, New Game Plan for Lou Ruvo Brain Institute Las Vegas: AD, Risk, ApoE—Tomm40 No Tomfoolery Las Vegas: Prevention Prominent at CTAD Las Vegas: 2020 Vision—AD Prevention in 11 Years? Clinical Trials on Alzheimer’s Disease 2009
St. Louis: Scientists, Families Target Preclinical Detection, Trials
Earlier this month, researchers met to devote two intense days of talks and discussion to their goal of presymptomatic detection of Alzheimer disease...
Honolulu: Potential New Gene on the ALS List
Researchers at the University of Michigan reported today on a new gene they suspect of contributing to amyotrophic lateral sclerosis (ALS)...
American Society for Human Genetics Annual Meeting
Honolulu: Potential New Gene on the ALS List American Society for Human Genetics Annual Meeting
Ipsen Neuroscience Colloquium 2009
Paris: Macro-roles for MicroRNAs in the Life and Death of Neurons Ipsen Neuroscience Colloquium 2009
The Skinny on NFATs—Mediators of Aβ Toxicity?
Could NFATs play a role in Alzheimer disease (AD) pathology?...
Meet the First Published TDP-43 Mouse
There’s a new mouse in the lab for the study of amyotrophic lateral sclerosis (ALS)...
The AICD Test? Transgenic Mice Show Neurodegeneration
The carving up of the APP by the successive action of β- and γ-secretases liberates Aβ, but also yields a small intracellular fragment, AICD...
Medical Foods for Alzheimer's: Palatable Therapy or Snake Oil?
In the absence of truly effective treatments, and in the presence of a rapidly growing, dementia-prone population of elders, it's perhaps no surprise that people are increasingly open to products claiming even the slightest hint of promise, however u
Medical Foods—Food for Thought, But Think Twice
While the AD field awaits a bona fide drug that goes beyond temporary relief of symptoms, patients may be increasingly open to products claiming even the slightest hint of promise...
Research Brief: Glatiramer Slows Progression From High Risk to MS
A drug used to prevent relapse of multiple sclerosis can also prevent people at risk from developing the full disease, according to a report by The Lancet...
Medical Foods—Fallback Option for Elusive AD Drug Status?
Defined by the FDA in 1988, medical foods are a special class of therapeutic agent that fall somewhere in between unregulated food supplements and FDA-approved drugs...
Paris: Macro-roles for MicroRNAs in the Life and Death of Neurons
The simple story of gene transcription into messenger RNA (mRNA) and subsequent translation into a protein has recently become considerably more complicated...
Dimebon: Bright Star or Black Hole?
Dimebon appears as one bright light in a field of less-than-stellar clinical trial results of late...
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