Chaperone “Saves” Tau, Turning it into Toxic Oligomers
As heat shock protein and co-chaperone team up to shield tau from degradation, they create toxic oligomers.
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As heat shock protein and co-chaperone team up to shield tau from degradation, they create toxic oligomers.
The insoluble proteome from Alzheimer’s brains points to RNA processing proteins as a novel component of aggregates.
Fueling (or rekindling) controversy over anti-aging benefits of sirtuins, researchers report that Sirt1 lengthens lifespan in mice.
Without the protein beclin 1, rapacious microglia choke on amyloid β.
Researchers nabbed rare variants in Alzheimer’s genes by sequencing DNA from people with very high or very low levels of cerebrospinal fluid biomarkers.
Preliminary data from Parkinson’s Progression Markers Initiative suggests that cerebrospinal fluid biomarkers distinguish the most rapidly progressing form of Parkinson’s.