Fall Flurry of Letters Kicks Up Dust Around TREM2
The latest data on TREM2 confirm that a variant in the gene associates with AD, and link it to Parkinson’s, brain degeneration, and γ-secretase.
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The latest data on TREM2 confirm that a variant in the gene associates with AD, and link it to Parkinson’s, brain degeneration, and γ-secretase.
It’s a scenario familiar to many clinicians: A patient diagnosed with mild cognitive impairment asks if he or she will eventually develop Alzheimer’s disease.
Like a blue moon, could oligomeric amyloid-β in the cerebrospinal fluid (CSF) be too rare to be informative?...
Over the past year, chatter has been building about combination drug therapy as the "New New Thing" in Alzheimer’s disease research...
Neurofibrillary tangles of tau protein litter Alzheimer’s disease brains, but are they actually bad for neurons?...
Your health insurance may not cover brain amyloid scans anytime soon...
Since the identification of the major ALS and FTLD gene C9ORF72 more than a year ago, scientists have been hunting for clues as to how it promotes disease...
Researchers report that mutations in hnRNPA2B1 and hnRNPA1 cause amyotrophic lateral sclerosis and multisystem proteinopathy...
White blood cells age quickly in post-menopausal women who carry the ApoE4 gene, but estrogen slows that decline...
Public funding is becoming so scarce that the DIAN researchers are increasingly asking industry to help...
Mutations that cause frontotemporal dementia may also predispose carriers to Alzheimer’s dementia...
Using stem cells to replace inhibitory neurons in the hippocampi of adult epileptic mice reduced hyperexcitability, seizures, and behavioral deficits...
It has become a complaint heard all too often—much academic research cannot be reproduced...
Scientists report that reducing hypertension may ward off amyloid pathology in people who have the ε4 version of the ApoE gene...
Eli Lilly and Company announced yesterday that they have terminated the Phase 2 trial of their BACE inhibitor LY2886721 due to liver abnormalities.