Synuclein Resists and Disrupts Autophagy
Could cranking up a cellular waste removal system help rid the brain of misfolded α-synuclein, the principle component of Lewy bodies found in neurodegenerative disorders such as Parkinson’s disease?
314 RESULTS
Sort By:
Could cranking up a cellular waste removal system help rid the brain of misfolded α-synuclein, the principle component of Lewy bodies found in neurodegenerative disorders such as Parkinson’s disease?
A method for examining the detailed structures of the intact brain with light microscopy debuts...
African Americans carrying a variant in a cholesterol-processing gene have double the risk for Alzheimer’s than non-carriers...
The last day of the meeting unfolded as is often the case at long conferences: Some of the most anticipated talks spilled their new data before sparse audiences...
When it comes to boosting cognition, any kind of activity may be better than nothing...
Researchers performed a genomewide association study (GWAS) to find markers associated with elevated levels of tau and phosphorylated tau in cerebrospinal fluid (CSF)...
Researchers debated how to put insights from longitudinal biomarker studies to use in the next wave of therapeutic trials, which increasingly include costly PET and MR scans...
Oligodendrocytes are joining astrocytes and microglia as members of a glial syndicate involved in the pathology of amyotrophic lateral sclerosis...
The 11th AD/PD Conference hosted a day-long exchange of new imaging data and discussion of current challenges for the research community in these two disorders...
Quick-and-Early IVIG Therapy: Hints of Promise? Anti-Amyloid Results Show Modest Benefits, Mild Side Effects Wrapping Up Enrollment, ADNI 2, PPMI Focus on Earlier Disease Drug Data Dash at AAN Annual Conference The ANN conference in San Diego covered such
There were so many new data on neurodegenerative disease trials at the recent AAN meeting that organizers crammed some of them into a session of three-minute talks...
Disrupted sleep-wake cycles often accompany neurodegeneration, but scientists are unsure why...
Scientists quipped about Florence as a fitting setting for what they perceive to be a resurgence of the amyloid hypothesis after a beleaguered period of setbacks...
The Alzheimer’s Disease Neuroimaging Initiative steering committee gathered to exchange the latest developments in ADNI 2...
Scientists continue to squeeze every last bit of information out of Phase 3 trials for anti-amyloid antibodies solanezumab and bapineuzumab...