ApoE Does Not Bind Aβ, Competes for Clearance
Rather than sequestering Aβ to prevent its clearance from the brain, ApoE may indirectly block the peptide’s path to breakdown...
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Rather than sequestering Aβ to prevent its clearance from the brain, ApoE may indirectly block the peptide’s path to breakdown...
A new recipe for cooking up cholinergic neurons from stem cells may help researchers study what goes wrong with these cells in Alzheimer’s disease...
When leaky blood vessels damage the brain, the organ’s stem cell niche dispatches a specialist crew of astrocytes to stop the bleeding...
Mutations that cause frontotemporal dementia may also predispose carriers to Alzheimer’s dementia...
As DIAN’s Scope Widens, Funding Narrows Dominantly Inherited Alzheimer Network Pharma Consortium Meeting 2013
Public funding is becoming so scarce that the DIAN researchers are increasingly asking industry to help...
A newly developed active amyloid-β vaccine removes Aβ from mouse brains while reducing inflammation and improving cognition...
One of the top Parkinson’s disease risk genes, GBA1, appears to be an even bigger risk factor for the related synucleinopathy dementia with Lewy bodies...
Therapies for amyotrophic lateral sclerosis (ALS) have proven hard to develop, in part because of inadequate disease models...
Researchers showed new data on how a therapeutic Aβ antibody their company had licensed from the Swiss biotech Neurimmune was measuring up...
You could say the concept that endogenous proteins in the body can misfold, aggregate, and spread disease from cell to cell has created infectious enthusiasm for drug development...
Eli Lilly and Company announced today that it has acquired the tau PET tracer program developed by Siemens Medical Solutions USA, Inc....
Could amyloid-beta fibrils—which form the hallmark plaques of Alzheimer’s disease (AD)—actually protect the brain?...
How do Aβ oligomers cause synapses to wither in Alzheimer’s disease?...
Imagine a remote control that manipulates specific neurons in a mouse's brain while it scurries about its cage getting on with normal rodent business...