Blind Flies Reveal Novel Neuroprotective Role for NAD Synthase
The NAD synthesizing protein nicotinamide mononucleotide adenylyltransferase (Nmnat) got the attention of neuroscience researchers as...
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The NAD synthesizing protein nicotinamide mononucleotide adenylyltransferase (Nmnat) got the attention of neuroscience researchers as...
Two new papers reveal how environmental influences can directly affect the activity of the APP-processing enzymes β-secretase (BACE1) and γ-secretase...
When it comes to pathological variations in the human genome, single nucleotide polymorphisms have taken their fair share of the heat...
Many researchers are acquainted with Arc/Arg3.1 as a marker of neuronal activity in the brain. The gene is induced by...
Trauma suffered at an early age can end up taking a toll later in life. Might the same hold true...
SfN Satellite Symposium: Neurotoxic Mechanisms in Alzheimer Disease SfN and More: Two Faces of TGF-β Revealed by Dead End Receptor SfN: Aβ Conformation and Location Figure in Toxicity SfN: The Old and the New—BACE and Cathepsin B Share the β-secretase Sta
A lively platter of slide talks on APP processing and β-secretase (BACE) activities yielded a few interesting tidbits on the...
Perhaps some good can come from the Alzheimer’s Disease Anti-inflammatory Prevention Trial (ADAPT)...
Tuebingen: Researchers Reminisce, Predict at Alzheimer Centennial Tuebingen: The Man Behind the Eponym Alzheimer 100 Centennial
Everyone with even a passing interest in Alzheimer disease has seen a sepia-toned photograph of its namesake like the one...
At this year’s annual meeting of the Society for Neuroscience, a grab bag of studies on the amyloid-β peptide highlighted some outstanding questions...
On Saturday, 3 November, 1906, Alois Alzheimer traveled from Munich, where he lived and worked, to Tuebingen. That afternoon...
Alzheimer Disease, Aging, and the Immune System Synaptic Function in Aging and AD High-throughput Assays (Application of OMICS to AD) Recommendations for Future Research Enabling Technologies for Alzheimer Disease Research: 2006 Bar Harbor Workshop
Two recent studies are changing traditional ideas about transcriptional regulation....
γ-secretase may have been one of the first intramembrane proteases to be described, but since its discovery...