Brain of First PIB-Imaged Patient Yields Clues to Alzheimer’s Disease
Imaging techniques promise to revolutionize the diagnosis of Alzheimer’s and other neurodegenerative diseases...
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Imaging techniques promise to revolutionize the diagnosis of Alzheimer’s and other neurodegenerative diseases...
The human genome is littered with scraps of millennia-old retroviruses, which hopped in, never hopped back out, and now pass from parents to children...
Speakers focused on the Coalition Against Major Diseases’ goal of garnering approval for biomarkers in AD drug development...
DC: CAMD Convenes Stakeholders to Reform Alzheimer’s Trials DC: Standard Data—Music to Regulators’ Ears DC: Shared Pain Is Lessened—Open-Trial Data Gain AD Model DC: Biomarkers, Parkinson’s—CAMD Needs All Hands on Deck Trial failure after trial failure: D
When a clinical trial comes up short, typically the data gets parked at the pharmaceutical company and the FDA...
The Coalition Against Major Diseases started one and a half years ago to develop tools that could improve drug development...
There lies an important, if obscure, area of AD coordination and regulatory work to improve a fledgling drug program’s chance at success...
As shocked researchers notify each other privately, the Alzforum editors are saddened to inform the community at large that Mark Smith died last Sunday...
In hunting for mutations that cause ALS, researchers discovered that VCP mutations, long thought to spare the spine, are instead a cause of inherited ALS...
Whenever scientists start looking at ways to maintain memory, some of the same names keep cropping up...
A study suggests that people at genetic risk for AD can show disrupted functional connections in the default-mode network—even without much detectable brain amyloid...
Many scientists now believe that Alzheimer’s disease attacks first at synapses...
The deafening buzz of firing neurons can drop to a dull hum if too much Aβ collects in the brain...
San Diego: What—3 Percent? Money Woes Trump Science at SfN San Diego: Tau Oligomer Antibodies Relieve Motor Deficits in Mice San Diego: TDP-43 Targets Loom Large—But Where’s the Bull’s Eye? San Diego: Pilin’ on the Pyro, Aβ Going Rogue San Diego: ALS Rese
In an ideal future, physicians would diagnose people with incipient Alzheimer’s disease long before memory problems appear...