Can Adaptive Trials Ride to the Rescue?
AD researchers are getting curious about an innovative type of trial design that is showing success in cancer and in medical device development...
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AD researchers are getting curious about an innovative type of trial design that is showing success in cancer and in medical device development...
A collective push is for therapeutic trials to start within the next two years in three different types of patients...
Recent findings have strengthened the scientific underpinning of the Alzheimer’s Prevention Initiative...
Researchers led by Dennis Selkoe offer what he considers the “cleanest, best-controlled evidence to date” for the toxicity of small amyloid-β oligomers...
Scientists have designed the “RatCAP,” a tiny positron emission tomography system for whole-brain imaging of freely moving rodents...
Murderers often incite others to do the same; molecular killers may be no exception...
What has the Alzheimer’s Prevention Initiative accomplished this past year?...
The protein SMN, which causes spinal muscular atrophy when mutated, orchestrates interactions between RNAs and splicing factors in the nucleus...
If you follow Alzheimer’s disease research at all, chances are you have heard of the families in the South American nation of Colombia...
TDP-43 scouts the nucleus like a roving film editor, splicing out introns from a slew of target RNAs...
The protein survival motor neuron (SMN) is missing in children with spinal muscular atrophy...
Since discovering it as a gene for frontotemporal lobar degeneration, scientists have puzzled over what progranulin does in the central nervous system...
Touchscreen technology has come to the rodent world...
Researchers have shown that overexpression of the molecule protein kinase Mζ (PKMζ), can strengthen memories long after they have formed...
Beyond age, the next biggest risk factor for late-onset Alzheimer’s disease is having the disorder in one’s pedigree, especially on Mom’s side...