Staying Alive: Freed of a Single Gene, Severed Axons Defy Death
Researchers report that it is possible to interrupt Wallerian degeneration by deleting a single gene...
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Researchers report that it is possible to interrupt Wallerian degeneration by deleting a single gene...
Researchers have published a new way to tackle a cell death enzyme that causes neurodegeneration and may lead to Alzheimer's, Huntington's, and other diseases...
In the fight against Alzheimer's disease (AD), the researcher may just be heard the loudest...
Rescuing motor neurons improves symptoms in mouse models of spinal muscular atrophy (SMA), but the animals do not live any longer than untreated controls...
It was not straightforward, but researchers have managed to knock out the essential, ubiquitous TDP-43 gene in mouse motor neurons...
Regulators and industry scientists, and other steering committee members from the FTSG submitted questions to the U.S. Food and Drug Administration...
Having a few excess polyglutamine codons—but not a lot—in the gene ataxin-2 predisposes a person to ALS, and scientists are just starting to figure out how...
Nursemaid oligodendrocytes care for neuronal axons not only by wrapping them in insulating myelin, but also by feeding them lactate...
Beth Stevens, Children’s Hospital, Boston, was one of 96 scientists and engineers who received Presidential Early Career Award for Scientists and Engineers...
Researchers report that AD-associated decline slows with advancing age, while “normal” aging-associated decline picks up...
What can big data do for medicine?...
The crimes of soluble Aβ continue to grow...
Researchers have discovered a gene that adjusts the course of amyotrophic lateral sclerosis, a fatal and rapidly progressing neurodegenerative disease...
Limiting caloric intake by 20 to 30 percent has been found to extend longevity in every creature from yeast to mammals, but can it make humans live longer—and healthier?...
Circadian rhythms are off in AD, illustrated in part by "sundowning," in which patients get confused and agitated late in the day and into the night...