Number 107: MicroRNA Gets to First BACE in AD Brain
The discovery of microRNAs (miRNAs) opened a door on a previously unsuspected world of genetic regulation...
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The discovery of microRNAs (miRNAs) opened a door on a previously unsuspected world of genetic regulation...
Scientists worldwide now perform amyloid imaging on scores of research participants to figure out how Aβ buildup relates to other markers of neurodegeneration...
If a shortage of iron harms development, yet having too much is linked to cognitive decline and neurodegeneration, what’s the lowdown on how this metal influences brain health?...
Since the approval of cholinesterase inhibitors and memantine, no new therapy for Alzheimer’s disease has passed the clinical trial litmus test...
Brain imaging has emerged as perhaps the most promising source to date of an antecedent marker for Alzheimer's disease...
Findings reported in tomorrow’s issue of Nature raise the tantalizing possibility of using vaccination to prevent or ameliorate Alzheimer’s disease. In the study, by Dale Schenk and colleagues at Elan Pharmaceuticals...
Clinical testing of ACC-001, Elan’s second-generation Aβ vaccine, is back on track...
Are you sometimes tempted to view APP and presenilin merely as raw material and machine for Aβ production, respectively? If so, think again, because that narrow spotlight is opening up to a broader understanding of how these two proteins function and might contribute to Alzheimer’s...
The regulation of neuronal plasticity and regeneration in the CNS is an aspect of Alzheimer’s disease that often has to compete with the big stars, such as amyloid or presenilin, for attention...
Researchers have suspected retroviruses to play a role in amyotrophic lateral sclerosis (ALS) since the 1960s, when poliomyelitis was proposed to contribute to progression of the disease...
What if all it took was a little sugar—not to make some other medicine go down, but as a therapy in itself for Huntington's disease? This is the promise of an article published...
In the genetics of late-onset Alzheimer disease, ApoE is the big fish...
The Wellcome Trust announced this week that it will fund what it describes as the largest ever Alzheimer’s gene study...
Read about this update of Martin Schwab's efforts to rekindle spinal cord regeneration with antibodies against the growth inhibitor nogo.
Among the strategies currently being pursued for treatment of Alzheimer disease (AD), inhibiting...