Neurodegeneration—A Developmental Problem?
Trauma suffered at an early age can end up taking a toll later in life. Might the same hold true...
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Trauma suffered at an early age can end up taking a toll later in life. Might the same hold true...
SfN Satellite Symposium: Neurotoxic Mechanisms in Alzheimer Disease SfN and More: Two Faces of TGF-β Revealed by Dead End Receptor SfN: Aβ Conformation and Location Figure in Toxicity SfN: The Old and the New—BACE and Cathepsin B Share the β-secretase Sta
A lively platter of slide talks on APP processing and β-secretase (BACE) activities yielded a few interesting tidbits on the...
Perhaps some good can come from the Alzheimer’s Disease Anti-inflammatory Prevention Trial (ADAPT)...
Tuebingen: Researchers Reminisce, Predict at Alzheimer Centennial Tuebingen: The Man Behind the Eponym Alzheimer 100 Centennial
Everyone with even a passing interest in Alzheimer disease has seen a sepia-toned photograph of its namesake like the one...
At this year’s annual meeting of the Society for Neuroscience, a grab bag of studies on the amyloid-β peptide highlighted some outstanding questions...
On Saturday, 3 November, 1906, Alois Alzheimer traveled from Munich, where he lived and worked, to Tuebingen. That afternoon...
Alzheimer Disease, Aging, and the Immune System Synaptic Function in Aging and AD High-throughput Assays (Application of OMICS to AD) Recommendations for Future Research Enabling Technologies for Alzheimer Disease Research: 2006 Bar Harbor Workshop
Two recent studies are changing traditional ideas about transcriptional regulation....
γ-secretase may have been one of the first intramembrane proteases to be described, but since its discovery...
This past August, Alzheimer disease researchers met with colleagues from other fields and with foundation and NIH representatives in Bar Harbor, Maine, at the sixth annual workshop on Enabling Technologies for Alzheimer Disease Research.
To what extent is AD an acceleration of normal aging? This decades-old question receded in favor of the view that AD is a separate process from normal aging when studies showed that patterns of neuronal loss are different in aging and AD.
Genomic/proteomic/metabolomics (OMICS) research in AD remains in its infancy. Most studies stall after discovering lists of hundreds of genes whose expression changes in the chosen comparison.
Recommendations for future research from the Enabling Technologies for Alzheimer's Disease Research in Bar Harbor (2006).