Enhancing glutamate transport partially restores neural function in mice.
PET scans detect activated glial cells in current and recently retired professional football players up to 21 years after their last concussion.
Friends and colleagues grapple with the loss of this young investigator.
Insulin delivered directly to the brain does nothing to Aβ in an AD mouse model, complicating the relationship between diabetes and Alzheimer’s.
Evidence from a nationally representative sample suggests a 12-year drop in age-specific risk of dementia.
Eli Lilly has given up on regulatory submission for mild AD, but leaves door open to seeking approval for earlier disease stages if three ongoing studies succeed.
Strains injected into mouse brain seed tau aggregation at different rates and in different regions of the brain.
Using a new, quantitative MRI method, researchers find accelerated myelin deterioration in preclinical Alzheimer’s disease.
This new inhibitor, which only works once phosphorylated by GSK3, reduced amyloid load and prevented cognitive deficits in an AD mouse model.
At least one phosphate tag may quell Aβ excitotoxicity.
The wireless implant converts signals from the patient’s motor cortex into type. This is the first such device to be used in a home setting.
Drawing on longitudinal ADNI data, a new study suggests that the degeneration of cholinergic neurons in the basal forebrain kicks off the neurodegenerative cascade of AD.
Fluselenamyl avoids white matter and binds diffuse plaques
Two international initiatives compile metadata from aging and AD studies into huge searchable catalogs in hopes of speeding research progress.
Before any other changes, the fatty coating on peripheral nerve fibers breaks apart, heralding their degeneration.