A novel mutation frays mitochondrial DNA and impedes ATP synthesis in people with an ALS-FTD-like syndrome.
Several thousand people have used preimplantation genetic diagnosis to avoid passing on pathogenic mutations to their babies, but many families with a history of Alzheimer’s or related diseases remain unaware of this option.
Families considering PGD to avoid passing on disease genes face obstacles such as high cost and invasive procedures.
Researchers retract two papers that claimed a quick dunk in acid turns mature mouse lymphocytes into pluripotent cells.
An award-winning film follows a social worker set on bringing music to people with dementia, and documents their unforgettable moments of awakening.
Antipsychotic medications repurposed to accelerate autophagy might prevent cellular toxicity associated with mutant TDP-43.
In fruit flies that model ALS, presynaptic vesicles gather in unusually large clumps, amplifying signaling at the neuromuscular junction. Does this promote disease?
Novartis Pharmaceuticals Corporation will partner with the Banner Alzheimer's Institute testing experimental preclinical therapies in the upcoming Alzheimer's Prevention Initiative ApoE4 study. The study complements the API ADAD trial.
The enzyme PARC acts as a survival factor in damaged neurons and cancer cells by targeting a pro-apoptotic protein for destruction.
Could tweaking methodologies improve amyloid diagnosis and tracking?
Researchers will have full access to a gargantuan genetic meta-analysis on the newly revamped PDGene database.
Québec: Stem Cells in ALS Update Québec: Transporters, Antibodies Offer Potential ALS Therapies Québec: STOMPing on Inclusions May Reveal their True Identity Québec: Chromogranins Help SOD1 Do Its Dirty Work Researchers need to meet each year to advance ...
Meet the New Progressive Tauopathy: CTE in Athletes, Soldiers Boxing: Study of Human Model for CTE Enters Second Round CTE: Trauma Triggers Tauopathy Progression Do Tau "Prions" Lead the Way From Concussions to Progression? CTE Needs Consensus ...
Honolulu: So Far, So Good in Stem Cell Safety Study for ALS American Academy of Neurology: 2011 Annual Meeting ...
New data strengthens the evidence that dementia risk is dropping in developed countries, possibly due to better education and heart health.