Paris: Studies Strengthen Link Between Brain Injury and Dementia
Some studies have shown that athletes who suffer repeated concussions develop a form of brain degeneration, different from AD, known as chronic traumatic encephalopathy...
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Some studies have shown that athletes who suffer repeated concussions develop a form of brain degeneration, different from AD, known as chronic traumatic encephalopathy...
In the fall of 2009, a large quality control (QC) program started comparing measurements of cerebrospinal fluid (CSF) biomarkers from labs across the world...
One French research initiative <em>par excellence</em> is the European Alzheimer's Disease Initiative (EADI)—but many other efforts also stood out...
President Sarkozy updated a packed hall on the Republic’s National Plan on Alzheimer's and related diseases that his administration implemented for the years 2008 to 2012...
With the buzz surrounding amyloid-targeting therapies, it is easy to lose sight of the fact that other treatments are being tested as well...
Last August, Eli Lilly and Company halted Phase 3 clinical trials of semagacestat after finding that patients on the medication fared worse than those on placebo...
After disappointing trial results for Alzheimer’s disease drugs, all eyes are on the Phase 3 clinical trials of two monoclonal antibodies to Aβ...
Apolipoprotein E (ApoE) gene alleles are the strongest genetic modulators of late-onset Alzheimer's disease (AD) risk...
As immune-based therapies targeting Aβ and tau are beginning to show promise for the treatment of Alzheimer’s, what about other disorders of the nervous system?...
Targeting extracellular Aβ with immunotherapy is one thing, but could antibodies even drive the clearance of tau, a predominantly intracellular protein?...
With potential immunotherapeutics mushrooming, Lars Lannfelt’s catalogue of antibodies might rival Linnaeus’s one of plants...
Attendees bonded over a common research interest—the protein tau and its role in neurodegeneration...
Though amyloid-β and tau stand as the pathological hallmarks of AD, only recently have scientists gained insight into how the two could be linked mechanistically...
Given its correlation with Alzheimer’s disease progression, tau hyperphosphorylation has long commanded the field’s attention...
In San Francisco, attendees discussed how tau goes awry...