Research Brief: From Fibroblast to Neuron in One Easy Step
It’s time to cut out the middleman—why go from fibroblasts, to induced pluripotent stem cells, to neurons, if one can skip straight to the payload?...
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It’s time to cut out the middleman—why go from fibroblasts, to induced pluripotent stem cells, to neurons, if one can skip straight to the payload?...
Though ApoE4 genotype has for years topped the list of genetic risk factors for AD, scientists grapple with how this allele makes people more prone to AD...
In an organ as highly vascular as the brain, optimal performance depends on keeping the plumbing shipshape...
When it comes to the synaptic toxicity and cognitive dysfunction in AD, a preponderance of evidence points to soluble oligomers of Aβ peptides as the main villains...
The Keystone Symposium at Copper Mountain, Colorado, was convened to discuss therapeutic approaches to Alzheimer disease besides those that target amyloid-β...
TDP-43, normally a mild-mannered nuclear protein, morphs into a cytoplasmic super villain in TDP-43 proteinopathies...
For stem cell therapies to work, it is not enough for a new neuron to settle down in the brain...
Researchers have, by and large, assumed that Aβ starts aggregating outside the cell...
Two studies revive the notion that it might be possible, quite literally, to catch a whiff of neurodegenerative disease before the body and mind slip away for good...
Through their research participation, the Reiswig extended family made possible the identification of presenilin 2 on chromosome 1...
The Alzforum presents a selection of some of the top ALS trial news of 2009—and looks ahead to 2010 and beyond...
<em>Drosophila</em> geneticists with an interest in neurodegeneration can now avail themselves of a new insect model...
If your lab has been scrimping and saving lately, you are not alone...
Bending to joint pressure from Congress, doctors, and the media, the NFL recently took steps to protect players with head injuries and to bolster research...
Phone companies will love this one; a new paper suggests that electromagnetic fields (EMFs) from cell phones can protect against AD—at least in mice...
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