All Comments by

  1. Paul Coleman on Presenilins and Alzheimer's disease: the role of A beta 42.
  2. Paul Coleman on Hyperphosphorylated tau in SY5Y cells: similarities and dissimilarities to abnormally hyperphosphorylated tau from Alzheimer disease brain.
  3. Hiroshi Mori on Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.
  4. Elliott Mufson on Heparin promotes beta-secretase cleavage of the Alzheimer's amyloid precursor protein.
  5. Hiroshi Mori on Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway.
  6. Richard Mayeux on Nasal administration of amyloid-beta peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease.
  7. Hiroshi Mori on Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau.
  8. Hiroshi Mori on Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain.
  9. Hiroshi Mori on Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.
  10. Paul Coleman on The regulation of phosphorylation of tau in SY5Y neuroblastoma cells: the role of protein phosphatases.
  11. Nikolaos K. Robakis on Apolipoprotein E isoform-specific reduction of extracellular amyloid in neuronal cultures.
  12. Hiroshi Mori on Phosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosis.
  13. John Olney on beta-Amyloid peptide-induced morphological changes coincide with increased K+ and Cl- channel activity in rat cortical astrocytes.
  14. Paul Coleman on Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective.
  15. Benjamin Wolozin on Dementia with Lewy bodies treated with rivastigmine: effects on cognition, neuropsychiatric symptoms, and sleep.