All Comments by Takaomi Saido

  1. Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo.
  2. Presymptomatic apolipoprotein E genotyping for Alzheimer's disease risk assessment and prevention.
  3. Time course of glucose metabolism in relation to cognitive performance and postmortem neuropathology in Met146Val PSEN1 mutation carriers.
  4. Power and pitfalls of the genome-wide association study approach to identify genes for Alzheimer's disease.
  5. Factors responsible for neurofibrillary tangles and neuronal cell losses in tauopathy.
  6. Dissociation of apolipoprotein E oligomers to monomer is required for high-affinity binding to phospholipid vesicles.
  7. Combinatorial Tau pseudophosphorylation: markedly different regulatory effects on microtubule assembly and dynamic instability than the sum of the individual parts.
  8. Two distinct amyloid beta-protein (Abeta) assembly pathways leading to oligomers and fibrils identified by combined fluorescence correlation spectroscopy, morphology, and toxicity analyses.
  9. What was lost in translation in the DHA trial is whom you should intend to treat.
  10. High ability of apolipoprotein E4 to stabilize amyloid-β peptide oligomers, the pathological entities responsible for Alzheimer's disease.
  11. Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain.
  12. Law and Disorder—APPswe Patent Suits Raise Ruckus Again
  13. Lack of brain-to-blood efflux transport activity of low-density lipoprotein receptor-related protein-1 (LRP-1) for amyloid-beta peptide(1-40) in mouse: involvement of an LRP-1-independent pathway.
  14. Structure-neurotoxicity relationships of amyloid beta-protein oligomers.
  15. Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease.