All Comments by Edward Koo
- APP transgenic mice Tg2576 accumulate Abeta peptides that are distinct from the chemically modified and insoluble peptides deposited in Alzheimer's disease senile plaques.
- Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice.
- FAD mutations in presenilin-1 or amyloid precursor protein decrease the efficacy of a gamma-secretase inhibitor: evidence for direct involvement of PS1 in the gamma-secretase cleavage complex.
- Molecular neuropathology of transgenic mouse models of Down syndrome.
- Preimplantation diagnosis for early-onset Alzheimer disease caused by V717L mutation.
- Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease.
- Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins.
- Head circumference and incident Alzheimer's disease: modification by apolipoprotein E.
- Environmental enrichment slows disease progression in R6/2 Huntington's disease mice.
- Role of the omentum in the treatment of Alzheimer's disease.
- Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta.
- Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains.
- Absence of cognitive impairment or decline in preclinical Alzheimer's disease.
- Imaging hippocampal function across the human life span: is memory decline normal or not?
- Volumetric MRI study of the caudate nucleus in patients with dementia with Lewy bodies, Alzheimer's disease, and vascular dementia.