All Comments by Nikolaos K. Robakis

  1. C-terminal maturation fragments of presenilin 1 and 2 control secretion of APP alpha and A beta by human cells and are degraded by proteasome.
  2. Melatonin protects hippocampal neurons in vivo against kainic acid-induced damage in mice.
  3. Rapid tau protein dephosphorylation and differential rephosphorylation during cardiac arrest-induced cerebral ischemia and reperfusion.
  4. Increased levels of apolipoprotein D in cerebrospinal fluid and hippocampus of Alzheimer's patients.
  5. Carnosine, a protective, anti-ageing peptide?
  6. Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity.
  7. Somatic mutation analysis of the APP and Presenilin 1 and 2 genes in Alzheimer's disease brains.
  8. Detection of neuritic plaques in Alzheimer's disease by magnetic resonance microscopy.
  9. Phosphatidylinositol and inositol involvement in Alzheimer amyloid-beta fibril growth and arrest.
  10. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology.
  11. Laminin inhibits Abeta42 fibril formation in vitro.
  12. Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease.
  13. Modification of tau to an Alzheimer's type protein interferes with its interaction with microtubules.
  14. Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease.
  15. alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies.