All Comments by Nikolaos K. Robakis

  1. Somatic mutation analysis of the APP and Presenilin 1 and 2 genes in Alzheimer's disease brains.
  2. Detection of neuritic plaques in Alzheimer's disease by magnetic resonance microscopy.
  3. Phosphatidylinositol and inositol involvement in Alzheimer amyloid-beta fibril growth and arrest.
  4. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology.
  5. Laminin inhibits Abeta42 fibril formation in vitro.
  6. Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease.
  7. Modification of tau to an Alzheimer's type protein interferes with its interaction with microtubules.
  8. Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease.
  9. alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies.
  10. Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype.
  11. Early amyloid deposition in the medial temporal lobe of young Down syndrome patients: a regional quantitative analysis.
  12. A familial case of Alzheimer's disease without tau pathology may be linked with chromosome 3 markers.
  13. Striation is the characteristic neuritic abnormality in Alzheimer disease.
  14. Assembly of paired helical filaments from mouse tau: implications for the neurofibrillary pathology in transgenic mouse models for Alzheimer's disease.
  15. Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis.