All Comments by Nikolaos K. Robakis

  1. Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease.
  2. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology.
  3. Laminin inhibits Abeta42 fibril formation in vitro.
  4. alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies.
  5. Modification of tau to an Alzheimer's type protein interferes with its interaction with microtubules.
  6. Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease.
  7. A familial case of Alzheimer's disease without tau pathology may be linked with chromosome 3 markers.
  8. Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype.
  9. Early amyloid deposition in the medial temporal lobe of young Down syndrome patients: a regional quantitative analysis.
  10. Assembly of paired helical filaments from mouse tau: implications for the neurofibrillary pathology in transgenic mouse models for Alzheimer's disease.
  11. Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis.
  12. Striation is the characteristic neuritic abnormality in Alzheimer disease.
  13. Interaction of Alzheimer beta-amyloid peptide(1-40) with lipid membranes.
  14. The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction.
  15. Genetic association of alpha2-macroglobulin with Alzheimer's disease in a Finnish elderly population.