All Comments by Nikolaos K. Robakis

  1. Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease.
  2. New susceptibility gene for Alzheimer's disease on chromosome 12?
  3. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease.
  4. Wide range of disease onset in a family with Alzheimer disease and a His163Tyr mutation in the presenilin-1 gene.
  5. Cell activation by glycated proteins. AGE receptors, receptor recognition factors and functional classification of AGEs.
  6. Prostaglandins act as neurotoxin for differentiated neuroblastoma cells in culture and increase levels of ubiquitin and beta-amyloid.
  7. Senile dementia with tangles (tangle predominant form of senile dementia).
  8. Expression profiles of multiple genes in single neurons of Alzheimer's disease.
  9. Genetic studies on chromosome 12 in late-onset Alzheimer disease.
  10. Treatment of Alzheimer's disease.
  11. Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons.
  12. Genetic association between alpha-2 macroglobulin and Japanese sporadic Alzheimer's disease.
  13. A protein kinase, PKN, accumulates in Alzheimer neurofibrillary tangles and associated endoplasmic reticulum-derived vesicles and phosphorylates tau protein.
  14. Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein.
  15. The HHQK domain of beta-amyloid provides a structural basis for the immunopathology of Alzheimer's disease.