All Comments by Nikolaos K. Robakis

  1. Society for Neuroscience Annual Meeting: Presenilins: An Overview
  2. Somatic mutation analysis of the APP and Presenilin 1 and 2 genes in Alzheimer's disease brains.
  3. Modification of tau to an Alzheimer's type protein interferes with its interaction with microtubules.
  4. Immunologic treatment of Alzheimer's disease.
  5. A familial case of Alzheimer's disease without tau pathology may be linked with chromosome 3 markers.
  6. Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.
  7. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease.
  8. Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid.
  9. Evidence that intramolecular associations between presenilin domains are obligatory for endoproteolytic processing.
  10. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology.
  11. Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein.
  12. alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies.
  13. Interaction of Alzheimer beta-amyloid peptide(1-40) with lipid membranes.
  14. Accumulation of SNAP-25 immunoreactive material in axons of Alzheimer's disease.
  15. A protein kinase, PKN, accumulates in Alzheimer neurofibrillary tangles and associated endoplasmic reticulum-derived vesicles and phosphorylates tau protein.