All Comments by Dominic Walsh

  1. Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism.
  2. Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein.
  3. Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity.
  4. Familial Alzheimer's disease mutations alter the stability of the amyloid beta-protein monomer folding nucleus.
  5. Role Reversal—AD Mouse Desperately Seeks CatB
  6. Aβ Star is Born? Memory Loss in APP Mice Blamed on Oligomer
  7. Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro.
  8. Hereditary cerebral hemorrhage with amyloidosis-Dutch type.
  9. Amyloid precursor-like protein 1 influences endocytosis and proteolytic processing of the amyloid precursor protein.
  10. Beta-secretase-cleaved amyloid precursor protein accumulates at actin inclusions induced in neurons by stress or amyloid beta: a feedforward mechanism for Alzheimer's disease.
  11. Atorvastatin, Vaccine Trial Data Published
  12. Varicose Axons: Traffic Jams Precede AD Pathology in Mice, Men
  13. An in vitro and in vivo study of early deficits in associative learning in transgenic mice that over-express a mutant form of human APP associated with Alzheimer's disease.
  14. FRETting Pays off—NSAIDs Target Presenilins, Reduce Aβ42
  15. A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60.