All Comments by John Hardy

  1. Identification of a novel family of presenilin homologues.
  2. A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain.
  3. Determinants of 4-repeat tau expression. Coordination between enhancing and inhibitory splicing sequences for exon 10 inclusion.
  4. SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease.
  5. Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo.
  6. Beta-amyloid precursor protein, ETS-2 and collagen alpha 1 (VI) chain precursor, encoded on chromosome 21, are not overexpressed in fetal Down syndrome: further evidence against gene dosage effect.
  7. Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition.
  8. Synucleins are a novel class of substrates for G protein-coupled receptor kinases.
  9. Effect of APOE genotype and promoter polymorphism on risk of Alzheimer's disease.
  10. Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta.
  11. Incidence of dementia and Alzheimer disease in 2 communities: Yoruba residing in Ibadan, Nigeria, and African Americans residing in Indianapolis, Indiana.
  12. Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people.