All Comments by Michael Wolfe
- Patricidal Protein? Aβ42 said to Inhibit Its Parent, γ-Secretase
- Patricidal Protein? Aβ42 said to Inhibit Its Parent, γ-Secretase
- Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4.
- Drilling Down into the CMS Aduhelm Decision—A Primer
- New Knock-In Mice Rapidly Accumulate Amyloid Plaques
- IFITM3 Forges Link Between Neuroinflammation and Aβ Production
- Social Distancing Shutters Alzheimer’s Research
- CryoEM γ-Secretase Structures Nail APP, Notch Binding
- New MO for Purported Anti-Amyloid Drug: Shielding APP from BACE?
- Paper Alert: Verubecestat Preclinical and Phase 1 Data Published
- G-Protein Receptor Knockout Rescues Several Models of Alzheimer’s
- G-Protein Receptor Knockout Rescues Several Models of Alzheimer’s
- Structural basis of human γ-secretase assembly.
- Trans-dominant negative effects of pathogenic PSEN1 mutations on γ-secretase activity and Aβ production.
- Trans-dominant negative effects of pathogenic PSEN1 mutations on γ-secretase activity and Aβ production.