All Comments by Ruth Itzhaki

  1. Herpes simplex virus type I induces the accumulation of intracellular β-amyloid in autophagic compartments and the inhibition of the non-amyloidogenic pathway in human neuroblastoma cells.
  2. Herpes Simplex and Alzheimer’s—Time to Think Again?
  3. HSV-1 promotes Ca2+ -mediated APP phosphorylation and Aβ accumulation in rat cortical neurons.
  4. Toronto: In Small Trial, IVIg Slows Brain Shrinkage
  5. CSF biomarkers of Alzheimer disease in HIV-associated neurologic disease.
  6. The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide.
  7. The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide.
  8. Herpes simplex virus type 1 DNA is located within Alzheimer's disease amyloid plaques.
  9. Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progression.
  10. The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.
  11. Isoform-specific effects of ApoE on HSV immediate early gene expression and establishment of latency.
  12. Disrupted spatial memory is a consequence of picornavirus infection.
  13. The Pathogen Hypothesis—Challenging the Primacy of Genetics in Late-Onset Alzheimer Disease.
  14. Neonatal infection induces memory impairments following an immune challenge in adulthood.
  15. Statins lower the risk of developing Alzheimer's disease by limiting lipid raft endocytosis and decreasing the neuronal spread of Herpes simplex virus type 1.