All Comments by David Holtzman

  1. ABCA1 Links Cholesterol and ApoE, But It May Not Be a Risk Factor for AD
  2. New Marker for AD on the Horizon?
  3. Alzheimer’s Vaccine: In Some Patients, at Least, It Might Just Work
  4. Amyloid Oligomer Antibody—One Size Fits All?
  5. Apolipoprotein E influences amyloid-beta clearance from the murine periphery.
  6. Amyloid Formation—One Amino Acid Can Make a Difference
  7. The Alzheimer's Vaccination Story, Continued
  8. More Evidence for Dynamic PolyQ Aggregates
  9. Antibodies to beta-amyloid decrease the blood-to-brain transfer of beta-amyloid peptide.
  10. The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration.
  11. Mutant Proteins—Is it Quality or Quantity that Counts?
  12. Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation.
  13. Local and systemic increase in lipid peroxidation after moderate experimental traumatic brain injury.
  14. Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice.
  15. Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.