All Comments by Lucia Chavez-Gutierrez
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- Patricidal Protein? Aβ42 said to Inhibit Its Parent, γ-Secretase
- Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4.
- Ratio of Short to Long Aβ Peptides: Better Handle on Alzheimer's than Aβ42/40?
- Field Loses GSM Developer Steven Wagner, 64
- Does More Aβ38 Mean Less Cognitive Decline in Alzheimer’s?
- iSILK Tracks Growth of Mouse Plaques at Peptide Level
- Stress-Associated Protein Modulates γ-Secretase to Make More Aβ
- Conformational Dynamics of Transmembrane Domain 3 of Presenilin 1 Is Associated with the Trimming Activity of γ-Secretase.
- BACE and γ-Secretase Form Mega-Complex that Processes APP
- CryoEM γ-Secretase Structures Nail APP, Notch Binding
- Probe Shines a Light on γ-Secretase Inhibitor’s Broad Reach
- γ-Secretase Revealed in Atomic Glory
- Structural basis of human γ-secretase assembly.
- Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease.
- Scientists Pinpoint γ-Secretase Modulator Binding Spot