All Comments by Paul Coleman

  1. Increased glyceraldehyde 3-phosphate dehydrogenase levels in the brain of patients with Down's syndrome.
  2. No hippocampal neuron or synaptic bouton loss in learning-impaired aged beta-amyloid precursor protein-null mice.
  3. Comparison of beta-protein/A4 deposits and Alz-50-stained cytoskeletal changes in the hypothalamus and adjoining areas of Alzheimer's disease patients: amorphic plaques and cytoskeletal changes occur independently.
  4. Hyperactivation of mitogen-activated protein kinase increases phospho-tau immunoreactivity within human neuroblastoma: additive and synergistic influence of alteration of additional kinase activities.
  5. Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures.
  6. Presymptomatic cognitive deficits in individuals at risk of familial Alzheimer's disease. A longitudinal prospective study.
  7. Pathologic correlates of apraxia in Alzheimer disease.
  8. Impaired proteolytic processing of presenilin-1 in chromosome 14-linked familial Alzheimer's disease patient lymphocytes.
  9. The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity.
  10. Neuropathological assessment of the lesions of significance in vascular dementia.
  11. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.
  12. Use of proxies to measure health and functional outcomes in effectiveness research in persons with Alzheimer disease and related disorders.
  13. Circulating autoantibodies to neuronal and glial filament proteins in autism.
  14. Link Between Education Level and AD Risk Strengthened