All Comments by Ilya Bezprozvanny

  1. Shielding Synaptic Glutamate Receptor from Aβ Preserves Memory in Mice
  2. Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus.
  3. Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease.
  4. ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43.
  5. Cytotoxicity of intracellular aβ42 amyloid oligomers involves Ca2+ release from the endoplasmic reticulum by stimulated production of inositol trisphosphate.
  6. First Crystal Structure of a Presenilin
  7. Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer's disease mice.
  8. Single-channel Ca(2+) imaging implicates Aβ1-42 amyloid pores in Alzheimer's disease pathology.
  9. A synaptic vesicle-associated Ca2+ channel promotes endocytosis and couples exocytosis to endocytosis.
  10. Presenilins, Ryanodine Receptors—Conspirators in Neurotransmission?
  11. Perpetrator and Savior—Presenilins Cut Both Ways
  12. NAADP mobilizes calcium from acidic organelles through two-pore channels.
  13. A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk.
  14. Mechanism of Ca2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating.
  15. Presenilin Loss of Function—Plan B for AD?