All Comments by Hiroshi Mori

  1. Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-pick type C cells.
  2. Discontinuous distribution of senile plaques within striate cortex hypercolumns in Alzheimer's disease.
  3. Alpha-secretase-derived product of beta-amyloid precursor protein is decreased by presenilin 1 mutations linked to familial Alzheimer's disease.
  4. Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau.
  5. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins.
  6. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.
  7. Alzheimer disease: quantitative H-1 MR spectroscopic imaging of frontoparietal brain.
  8. Complete genomic screen in late-onset familial Alzheimer's disease.
  9. Heparin-binding properties of the amyloidogenic peptides Abeta and amylin. Dependence on aggregation state and inhibition by Congo red.
  10. Mutation screening in exons 3 and 4 of alpha-synuclein in sporadic Parkinson's and sporadic and familial dementia with Lewy bodies cases.
  11. The effect of estrogen replacement therapy on cognitive function in women: a critical review of the literature.
  12. Presenilin 1 intronic polymorphism is not associated with Alzheimer type neuropathological changes or sporadic Alzheimer's disease.
  13. A nucleated assembly mechanism of Alzheimer paired helical filaments.
  14. The regulation of phosphorylation of tau in SY5Y neuroblastoma cells: the role of protein phosphatases.
  15. No hippocampal neuron or synaptic bouton loss in learning-impaired aged beta-amyloid precursor protein-null mice.