All Comments by Hiroshi Mori

  1. Laminin inhibits Abeta42 fibril formation in vitro.
  2. Intracellular inositol (1,4,5)-trisphosphate receptor levels are preserved in Alzheimer's disease platelets.
  3. Alzheimer's disease as proteolytic disorders: anabolism and catabolism of beta-amyloid.
  4. Corticobasal ganglionic degeneration and progressive supranuclear palsy presenting with cognitive decline.
  5. Lipoprotein-free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer's disease and Down's syndrome.
  6. Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein.
  7. Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles.
  8. Novel large apolipoprotein E-containing lipoproteins of density 1.006-1.060 g/ml in human cerebrospinal fluid.
  9. Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein.
  10. Contrasting role of presenilin-1 and presenilin-2 in neuronal differentiation in vitro.
  11. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.
  12. Structural analysis of Alzheimer's beta(1-40) amyloid: protofilament assembly of tubular fibrils.
  13. Sialylated human apolipoprotein E (apoEs) is preferentially associated with neuron-enriched cultures from APOE transgenic mice.
  14. Heparin oligosaccharides that pass the blood-brain barrier inhibit beta-amyloid precursor protein secretion and heparin binding to beta-amyloid peptide.
  15. Decreased beta-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.