All Comments by Hiroshi Mori

  1. Protective effects of idebenone and alpha-tocopherol on beta-amyloid-(1-42)-induced learning and memory deficits in rats: implication of oxidative stress in beta-amyloid-induced neurotoxicity in vivo.
  2. The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex.
  3. How to cope with Alzheimer's disease?
  4. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis of proteins in human cerebrospinal fluid.
  5. Okadaic acid-induced apoptosis in neuronal cells: evidence for an abortive mitotic attempt.
  6. Regionally specific neuronal expression of human APOE gene in transgenic mice.
  7. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
  8. Estrogens stabilize mitochondrial function and protect neural cells against the pro-apoptotic action of mutant presenilin-1.
  9. Free radicals and superoxide dismutase in blood of patients with Alzheimer's disease and vascular dementia.
  10. Genetic risk factors in Japanese Alzheimer's disease patients: alpha1-ACT, VLDLR, and ApoE.
  11. Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-pick type C cells.
  12. Discontinuous distribution of senile plaques within striate cortex hypercolumns in Alzheimer's disease.
  13. Alpha-secretase-derived product of beta-amyloid precursor protein is decreased by presenilin 1 mutations linked to familial Alzheimer's disease.
  14. Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau.
  15. The 118-135 peptide of the human prion protein forms amyloid fibrils and induces liposome fusion.