All Comments by Hiroshi Mori

  1. No association of presenilin-1 intronic polymorphism and Alzheimer's disease in Australia.
  2. E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.
  3. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.
  4. ApoE genotype is a risk factor in nonpresenilin early-onset Alzheimer's disease families.
  5. Oxidative metabolism in cultured fibroblasts derived from sporadic Alzheimer's disease (AD) patients.
  6. Cerebrovascular accumulation and increased blood-brain barrier permeability to circulating Alzheimer's amyloid beta peptide in aged squirrel monkey with cerebral amyloid angiopathy.
  7. Melatonin prevents beta-amyloid-induced lipid peroxidation.
  8. Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer.
  9. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology.
  10. Alpha-secretase-derived product of beta-amyloid precursor protein is decreased by presenilin 1 mutations linked to familial Alzheimer's disease.
  11. Effects of frontotemporal dementia FTDP-17 mutations on heparin-induced assembly of tau filaments.
  12. Age-related alteration of PKC, a key enzyme in memory processes: physiological and pathological examples.
  13. Intracerebral hemorrhage in two patients with Down's syndrome and cerebral amyloid angiopathy.
  14. Neuropathological assessment of the lesions of significance in vascular dementia.
  15. Bcl-2 and Bax protein expression in Alzheimer's disease.