All Comments by Hiroshi Mori

  1. Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer's disease, and apolipoprotein E-epsilon4/4 genotype.
  2. Immunoreactivity of presenilin-1 and tau in Alzheimer's disease brain.
  3. Laminin inhibits Abeta42 fibril formation in vitro.
  4. Intracellular inositol (1,4,5)-trisphosphate receptor levels are preserved in Alzheimer's disease platelets.
  5. Protein anatomy: C-tail region of human tau protein as a crucial structural element in Alzheimer's paired helical filament formation in vitro.
  6. Generation of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavage.
  7. Lipoprotein-free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer's disease and Down's syndrome.
  8. Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein.
  9. Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles.
  10. Novel large apolipoprotein E-containing lipoproteins of density 1.006-1.060 g/ml in human cerebrospinal fluid.
  11. Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein.
  12. Contrasting role of presenilin-1 and presenilin-2 in neuronal differentiation in vitro.
  13. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.
  14. Structural analysis of Alzheimer's beta(1-40) amyloid: protofilament assembly of tubular fibrils.
  15. Sialylated human apolipoprotein E (apoEs) is preferentially associated with neuron-enriched cultures from APOE transgenic mice.