All Comments by Hiroshi Mori

  1. Alzheimer's presenilin-1 mutation potentiates inositol 1,4,5-trisphosphate-mediated calcium signaling in Xenopus oocytes.
  2. Stable association of presenilin derivatives and absence of presenilin interactions with APP.
  3. Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?
  4. Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain.
  5. Inhibition of Alzheimer beta-fibrillogenesis by melatonin.
  6. Paired helical filament morphology varies with intracellular location in Alzheimer's disease brain.
  7. Modulation of nitric oxide production in human macrophages by apolipoprotein-E and amyloid-beta peptide.
  8. Apolipoprotein-E deficiency results in an altered stress responsiveness in addition to an impaired spatial memory in young mice.
  9. Cytochrome oxidase in Alzheimer's disease: biochemical, histochemical, and immunohistochemical analyses of the visual and other systems.
  10. Cerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease.
  11. Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase.
  12. Intracellular accumulation of detergent-soluble amyloidogenic A beta fragment of Alzheimer's disease precursor protein in the hippocampus of aged transgenic mice.
  13. GM1 ganglioside-bound amyloid beta-protein in Alzheimer's disease brain.
  14. Co-localization of truncated tau and DNA fragmentation in Alzheimer's disease neurones.
  15. Common core structure of amyloid fibrils by synchrotron X-ray diffraction.