All Comments by Edward Koo

  1. Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease.
  2. Role of the omentum in the treatment of Alzheimer's disease.
  3. APP transgenic mice Tg2576 accumulate Abeta peptides that are distinct from the chemically modified and insoluble peptides deposited in Alzheimer's disease senile plaques.
  4. Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease.
  5. A gene trap insertion reveals that amyloid precursor protein expression is a very early event in murine embryogenesis.
  6. Cortical inflammation in Alzheimer disease but not dementia with Lewy bodies.
  7. Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc.
  8. Treatment with controlled-release lovastatin decreases serum concentrations of human beta-amyloid (A beta) peptide.
  9. Use of bomb pulse carbon-14 to age senile plaques and neurofibrillary tangles in Alzheimer's disease.
  10. Copernicus revisited: amyloid beta in Alzheimer's disease.
  11. Absence of cognitive impairment or decline in preclinical Alzheimer's disease.
  12. Endoplasmic reticulum stress-induced cysteine protease activation in cortical neurons: effect of an Alzheimer's disease-linked presenilin-1 knock-in mutation.
  13. Head circumference and incident Alzheimer's disease: modification by apolipoprotein E.
  14. Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains.
  15. FAD mutations in presenilin-1 or amyloid precursor protein decrease the efficacy of a gamma-secretase inhibitor: evidence for direct involvement of PS1 in the gamma-secretase cleavage complex.