All Comments by Samuel Gandy

  1. Cognitive Decline in Young Football Player Tied to Extensive Brain Damage
  2. Could Bolstering the Retromer Thwart Alzheimer’s?
  3. Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study.
  4. Functional MRI Detects Brain Abnormalities in Former Football Players
  5. Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease.
  6. Not So Fast: Amyloid PET Needs More Data Before Insurance Pays
  7. Ironing Out Apoptotic Role for New APP-Binding Protein
  8. Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid.
  9. Depletion of GGA1 and GGA3 mediates postinjury elevation of BACE1.
  10. β-amyloid inhibits protein prenylation and induces cholesterol sequestration by impairing SREBP-2 cleavage.
  11. Testing the right target and right drug at the right stage.
  12. LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking.
  13. Neuronal activity regulates the regional vulnerability to amyloid-β deposition.
  14. Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma.
  15. Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated.